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Nontuberculous Mycobacterial Disease (NTM) - Extrapulmonary


There are more than 100 species of NTM, but in the U.S. the most frequently isolated species associated with disease are M. avium complex (MAC), M. marinum (skin and soft tissue infections), M. kansasii (southern states), and M. xenopi (states along the Canadian border). The class of rapidly growing myco­bacteria including M. abscessus, M. chelonae, and M. fortuitum are also important causes of NTM disease.
 
Extrapulmonary NTM disease manifests as cutaneous, bone, joint, lymph node, or central nervous system (CNS) disease. Cutaneous infections typically result from either direct inoculation during trauma, surgical or medical procedures, exposures to whirlpool baths, or other settings such as nail salons or tattoo proce­dures. Isolated lymphadenitis occurs in otherwise healthy children, generally under 5 years of age. Disseminated extrapulmonary disease generally only occurs in immunocompromised patients (e.g., HIV, transplant, cancer, end-stage renal disease, others) and typically results from infection via the gastrointestinal tract with hematogenous spread of organism.


Disease Reporting

Laboratories are to report all test results indicative of and specific for extrapulmonary nontuberculous my­cobacteria (NTM) within one working day.
 
See our disease reporting page for information on how to report and for telephone numbers of local health departments.
 
For County Health Departments: