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Leptospirosis Antibody, Total

Updated

10/5/2009

Other Names Ft. Bragg Fever
How to Order
Check the Leptospirosis box on the
Virology/Immunology Request (Form 42) 
Availability
All Clients
Methodology
Indirect Hemagglutination (IHA)
Performed
Weekly
Time to Reporting
1 to 6 working days after receipt
CPT Code
86720


Specimen Collection Details

Collection
One 7 ml red top tube or serum separator tube (SST).
Optimal Volume
Blood: 5-7 mL; Serum 1-2 mL
Minimum Volume
Blood: 2 mL; Serum 0.5 mL
Handling
After blood clots, keep specimen refrigerated until transport. DO NOT FREEZE if serum has not been removed. If possible remove the serum from the clot as soon as possible. Sample must be tested within 5 days of collection or frozen and trans- ported at -20°C. 
Transport
Refrigerated at 2-8° C.
Rejection Criteria
Severely lipemic, grossly hemolyzed, heat-inactivated or contaminated specimens; specimens received without proper patient identifiers on specimen tube and/or request form; and specimens received with requests without submitter information will be rejected.
Comments
Results should be correlated with clinical data. Acute titers may be delayed or substantially decreased by early, intensive antibiotic treatment. 
Reference Range: 
Titer <1:50    No antibody detected to
                     leptospirosis
Titer   1:50     Borderline Positive: evaluate
                     patient for clinical correlation with
                     active or recent leptospirosis and
                     repeat testing in 2-3 weeks.
Titer > 100     Positive for leptospiral antibody.
                     Evidence of active or recent
                     leptospirosis.