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Varicella (Chickenpox) (vaccine-preventable)


Varicella is usually a mild disease in healthy children.  Severe cases can cause infection leading to death. Varicella disease can cause more complications and severe infection as children enter adolescence and adulthood.  Childhood immunization is recommended.
Varicella Zoster Immune Globulin (VariZIG™) is  recommended for certain groups at high risk for severe disease after exposure to the varicella-zoster virus, for whom varicella vaccine is contraindicated and  within 10 days of exposure. VariZIG is indicated for:
  • Immunocompromised patients without evidence of immunity.
  • Newborn infants whose mothers have signs and symptoms of varicella around the time of delivery (i.e., 5 days before to 2 days after).
  • Hospitalized premature infants born at ≥28 weeks of gestation whose mothers do not have evidence of immunity to varicella.
  • Hospitalized premature infants born at <28 weeks of gestation or who weigh ≤1,000 g at birth, regardless of their mothers' evidence of immunity to varicella.
  • Pregnant women without evidence of immunity.

VariZIG can be ordered from FFF Enterprises (telephone, 800-843-7477; online at


See Also
  • CDC Vaccine Information Statements (English only)
  • CDC Vaccine Information Statements in other languages from the Immunization Action Coalition
  • Information on vaccination

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